The ACCE method: an approach for obtaining quantitative or qualitative estimates of residual confounding that includes unmeasured confounding
نویسندگان
چکیده
منابع مشابه
The ACCE method: an approach for obtaining quantitative or qualitative estimates of residual confounding
BACKGROUND Nonrandomized studies typically cannot account for confounding from unmeasured factors. METHOD A method is presented that exploits the recently-identified phenomenon of "confounding amplification" to produce, in principle, a quantitative estimate of total residual confounding resulting from both measured and unmeasured factors. Two nested propensity score models are construc...
متن کاملSensitivity analysis for interactions under unmeasured confounding.
We develop a sensitivity analysis technique to assess the sensitivity of interaction analyses to unmeasured confounding. We give bias formulas for sensitivity analysis for interaction under unmeasured confounding on both additive and multiplicative scales. We provide simplified formulas in the case in which either one of the two factors does not interact with the unmeasured confounder in its ef...
متن کاملUsing an instrumental variable to test for unmeasured confounding.
An important concern in an observational study is whether or not there is unmeasured confounding, that is, unmeasured ways in which the treatment and control groups differ before treatment, which affect the outcome. We develop a test of whether there is unmeasured confounding when an instrumental variable (IV) is available. An IV is a variable that is independent of the unmeasured confounding a...
متن کاملThe sign of the bias of unmeasured confounding.
Unmeasured confounding variables are a common problem in drawing causal inferences in observational studies. A theorem is given which in certain circumstances allows the researcher to draw conclusions about the sign of the bias of unmeasured confounding. Specifically, it is possible to determine the sign of the bias when monotonicity relationships hold between the unmeasured confounding variabl...
متن کاملSharp sensitivity bounds for mediation under unmeasured mediator-outcome confounding
It is often of interest to decompose the total effect of an exposure into a component that acts on the outcome through some mediator and a component that acts independently through other pathways. Said another way, we are interested in the direct and indirect effects of the exposure on the outcome. Even if the exposure is randomly assigned, it is often infeasible to randomize the mediator, leav...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: F1000Research
سال: 2015
ISSN: 2046-1402
DOI: 10.12688/f1000research.4801.2